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Projects

The IQ MPS Affiliate was established to provide a venue for appropriate cross-pharma collaboration and data sharing to facilitate the industry implementation and qualification of MPS models. The IQ MPS Affiliate issues Requests for Information and Requests for Proposals to solicit interest in collaborating on the characterization of microphysiological systems for use in drug development. Please see below for information on specific opportunities. 

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Gastrointestinal Microphysiological System Testing for Specific Contexts of Use in Drug Development - RFI & RFP CLOSED

The IQ MPS Affiliate seeks novel gastrointestinal MPS technology platforms with clear, mechanistically-based rationale that not only recapitulate the human intestinal environment in terms of functional capabilities, but also demonstrate improved clinical predictivity for key ADME endpoints and toxicological responses. A single model that addresses all responses, while desirable, is not the sole objective. Emphasis on endpoint-specific predictivity of clinical responses and proven utility will be the most critical for potential future adoption of these systems in drug discovery and development.

Download the RFI here.
 
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Kidney Microphysiological System Testing for Specific Contexts of Use in Drug Development - RFI & RFP CLOSED
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The IQ MPS Affiliate seeks novel kidney MPS technology platforms with clear, mechanistically-based rationale that not only recapitulate the human renal environment in terms of functional capabilities, but also demonstrate improved clinical predictivity for key ADME endpoints and toxicological responses. A single model that addresses all responses, while desirable, is not the sole objective. Emphasis on endpoint-specific predictivity of clinical response and proven utility will be most critical for potential future adoption of these systems in drug discovery and development. 
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Download the RFI here.
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